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PRAK Polyclonal Antibody, 20ul[BT-AP07383] In vitro Assessment The encoded protease (cathepsin G)

SKU: 72189994118

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PRAK Polyclonal Antibody, 20ul[BT-AP07383] In vitro Assessment The encoded protease (cathepsin G)The protein encoded by MAPKAPK5 (mitogen activated protein kinase activated protein kinase 5) is a tumor suppressor and member of the serine threonine kinase family. In response to cellular stress and proinflammatory cytokines, this kinase is activated through its phosphorylation by MAP kinases including MAPK1 ERK, MAPK14 p38 alpha, and MAPK11 p38 beta. The encoded protein is found in the nucleus but translocates to the cytoplasm upon phosphorylation

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Description

The encoded protease (cathepsin G) has a specificity similar to that of chymotrypsin C

RAD17 checkpoint clamp loader component shares strong similarity with DNA replication factor C (RFC)

Mutations in CEP135 are associated with autosomal recessive primary microcephaly-8

The encoded protein is primarily localized to the trans-Golgi network and is involved in maintaining pH homeostasis in organelles along the secretory and endocytic pathways

PRAK Polyclonal Antibody, 20ul[BT-AP07383] In vitro Assessment The encoded protease (cathepsin G)The protein encoded by MAPKAPK5 (mitogen activated protein kinase activated protein kinase 5) is a tumor suppressor and member of the serine threonine kinase family. In response to cellular stress and proinflammatory cytokines, this kinase is activated through its phosphorylation by MAP kinases including MAPK1 ERK, MAPK14 p38 alpha, and MAPK11 p38 beta. The encoded protein is found in the nucleus but translocates to the cytoplasm upon phosphorylation

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