GNAO Polyclonal Antibody, 100ul Nucleic Acid Isolation & Purification Multiple 5' alternatively spliced variants

Multiple 5' alternatively spliced variants

As a member of the endoplasmic reticulum protein family the encoded protein contains a Lys-Asp-Glu-Leu or KDEL motif located at the extreme C-terminus which prevents all endoplasmic reticulum resident proteins from being secreted

This gene encodes a member of the phosphatase and actin regulator protein family

while isoform 2 is detected only in lymph nodes

GNAO Polyclonal Antibody, 100ul Nucleic Acid Isolation & Purification Multiple 5' alternatively spliced variantsThe protein encoded by this gene represents the alpha subunit of the Go heterotrimeric G protein signal transducing complex. Defects in this gene are a cause of early onset epileptic encephalopathy. Two transcript variants encoding different isoforms have been found for this gene.