GFR Alpha-4 Polyclonal Antibody, 50ul Immunology The encoded protein acts as

The encoded protein acts as a receptor and binds to both soluble and immobilized hyaluronan

NLGN2 and NLGN3

and thus may play a regulatory role in PKA or retinoic acid induced neuronal differentiation

Defects in this gene are associated with isolated cleft palate and mental retardation

GFR Alpha-4 Polyclonal Antibody, 50ul Immunology The encoded protein acts asThe protein encoded by GFRA4 (GDNF family receptor alpha 4)is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol (GPI) linked cell surface receptor for persephin, and mediates activation of the RET tyrosine kinase receptor. GFRA4 is a candidate gene for RET associated diseases. Alternatively spliced transcript variants encoding different isoforms have been described for GFRA4.