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UVRAG Polyclonal Antibody, 20ul Pathway and Network Analysis Gene Ontology (GO) annotations related

SKU: 72919613443

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UVRAG Polyclonal Antibody, 20ul Pathway and Network Analysis Gene Ontology (GO) annotations relatedThis gene complements the ultraviolet sensitivity of xeroderma pigmentosum group C cells and encodes a protein with a C2 domain. The protein activates the Beclin1 PI(3)KC3 complex, promoting autophagy and suppressing the proliferation and tumorigenicity of human colon cancer cells. Chromosomal aberrations involving this gene are associated with left right axis malformation and mutations in this gene have been associated with colon cancer.

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Description

Gene Ontology (GO) annotations related to NKX2-4 include sequence-specific DNA binding

which binds to one of the components of the multiprotein editosome complex

and rearrangement of this gene that are associated with myxoid liposarcoma suggests a role in adipogenesis and mesenchymal differentiation

This gene is a protooncogene that encodes a protein tyrosine kinase involved in a variety of cellular processes| including cell division| adhesion| differentiation| and response to stress

UVRAG Polyclonal Antibody, 20ul Pathway and Network Analysis Gene Ontology (GO) annotations relatedThis gene complements the ultraviolet sensitivity of xeroderma pigmentosum group C cells and encodes a protein with a C2 domain. The protein activates the Beclin1 PI(3)KC3 complex, promoting autophagy and suppressing the proliferation and tumorigenicity of human colon cancer cells. Chromosomal aberrations involving this gene are associated with left right axis malformation and mutations in this gene have been associated with colon cancer.

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