TH(Phospho Ser62) Polyclonal Antibody, 20ul Enzymes Initiation of transcription by RNA

Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides

is strongly expressed in brain and testis and weakly expressed in liver

The protein encoded by this gene is a component of the histone deacetylase complex| which includes SIN3| SAP30| HDAC1| HDAC2| RbAp46| RbAp48| and other polypeptides

which translocates to the nucleus

TH(Phospho Ser62) Polyclonal Antibody, 20ul Enzymes Initiation of transcription by RNAThe protein encoded by this gene is involved in the conversion of tyrosine to dopamine. It is the rate limiting enzyme in the synthesis of catecholamines, hence plays a key role in the physiology of adrenergic neurons. Mutations in this gene have been associated with autosomal recessive Segawa syndrome. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.