ZIP7 Polyclonal Antibody, 100ul Primary Antibodies Alternate splicing of this gene

Alternate splicing of this gene results in multiple transcript variants encoding different isoforms

and the SH2 domain of GRB2

These autoantibodies are present in nearly 95% of patients with the autoimmune liver disease primary biliary cirrhosis (PBC)

It is highly conserved in vertebrates and most abundantly expressed in the brain

ZIP7 Polyclonal Antibody, 100ul Primary Antibodies Alternate splicing of this geneZinc transporter SLC39A7 encoded by SLC39A7 transports zinc from the Golgi and endoplasmic reticulum to the cytoplasm. This transport may be important for activation of tyrosine kinases, some of which could be involved in cancer progression. Therefore, modulation of the encoded protein could be useful as a therapeutic agent against cancer. Alternative splicing results in multiple transcript variants.