IP3 Receptor(Phospho Tyr353) Rabbit Polyclonal Antibody, 20ul Sealing Film Genome-wide association studies in some

Genome-wide association studies in some populations have found an association between polymorphisms in this gene and sporadic amyotrophic lateral sclerosis

Two transcript variants encoding distinct isoforms have been identified

Studies in rodents suggest that this protein is involved in the establishment of left-right asymmetry in early embryogenesis and in neural development in later embryogenesis

It has both 17alpha-hydroxylase and 17

IP3 Receptor(Phospho Tyr353) Rabbit Polyclonal Antibody, 20ul Sealing Film Genome-wide association studies in someThis gene encodes an intracellular receptor for inositol 1 4 5 trisphosphate. Upon stimulation by inositol 1 4 5 trisphosphate this receptor mediates calcium release from the endoplasmic reticulum. Mutations in this gene cause spinocerebellar ataxia type 15 a disease associated with an heterogeneous group of cerebellar disorders. Multiple transcript variants have been identified for this gene.