Raf-1 Polyclonal Antibody, 50ul[BT-AP13534] Cell Function Analysis This receptor contains an extracellular

This receptor contains an extracellular TRAIL-binding domain and a transmembrane domain

It forms a 1-to-1 noncovalent complex with glycoprotein Ib

Alternatively spliced transcript variants encoding different isoforms have been

Deficiencies in this gene can result in male pseudohermaphroditism

Raf-1 Polyclonal Antibody, 50ul[BT-AP13534] Cell Function Analysis This receptor contains an extracellularThis gene is the cellular homolog of viral raf gene (v raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine threonine specific protein kinases, ERK1 and ERK2.