c-Cbl(Phospho-Tyr731) Rabbit Polyclonal Antibody, 20ul Apoptosis & Autophagy and is involved in the

and is involved in the folding and assembly of proteins in the ER

a proline-rich region

Mutations in this gene are associated with Barrett esophagus and esophageal adenocarcinoma

These proteins are characterized by the presence of seven alpha-helical transmembrane domains

c-Cbl(Phospho-Tyr731) Rabbit Polyclonal Antibody, 20ul Apoptosis & Autophagy and is involved in theThis gene is a proto oncogene that encodes a RING finger E3 ubiquitin ligase. The encoded protein is one of the enzymes required for targeting substrates for degradation by the proteasome. This protein mediates the transfer of ubiquitin from ubiquitin conjugating enzymes (E2) to specific substrates. This protein also contains an N terminal phosphotyrosine binding domain that allows it to interact with numerous tyrosine phosphorylated substrates and