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FAN Rabbit Polyclonal Antibody, 100ul Immune Cell Analysis PMF1 (polyamine-modulated factor 1)

SKU: 74294563723

4.6
USD123.75 USD171.75

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FAN Rabbit Polyclonal Antibody, 100ul Immune Cell Analysis PMF1 (polyamine-modulated factor 1)This gene encodes a WD repeat protein that binds the cytoplasmic sphingomyelinase activation domain of the 55kD tumor necrosis factor receptor. This protein is required for TNF mediated activation of neutral sphingomyelinase and may play a role in regulating TNF induced cellular responses such as inflammation. Alternative splicing results in multiple transcript variants.

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Description

PMF1 (polyamine-modulated factor 1)

subcellular location:Enriched in lipid rafts

|subunit:Binds to the receptor tyrosine kinases EPHA2| EPHA4| EPHA5| EPHA6 and EPHA7

FAT10 is inducible by interferon-g and tumor necrosis factor a (TNF)

FAN Rabbit Polyclonal Antibody, 100ul Immune Cell Analysis PMF1 (polyamine-modulated factor 1)This gene encodes a WD repeat protein that binds the cytoplasmic sphingomyelinase activation domain of the 55kD tumor necrosis factor receptor. This protein is required for TNF mediated activation of neutral sphingomyelinase and may play a role in regulating TNF induced cellular responses such as inflammation. Alternative splicing results in multiple transcript variants.

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