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PCB Polyclonal Antibody, 50ul Bottles As is typical for genes

SKU: 74576440127

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PCB Polyclonal Antibody, 50ul Bottles As is typical for genesPC encodes pyruvate carboxylase, which requires biotin and ATP to catalyse the carboxylation of pyruvate to oxaloacetate. The active enzyme is a homotetramer arranged in a tetrahedron which is located exclusively in the mitochondrial matrix. Pyruvate carboxylase is involved in gluconeogenesis, lipogenesis, insulin secretion and synthesis of the neurotransmitter glutamate. Mutations in this gene have been associated with pyruvate carboxylase

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Description

As is typical for genes encoding ribosomal proteins

According to PubMed:97066888

2001 [PubMed 12063393])

Mutations in EPHA2 are the cause of certain genetically-related cataract disorders

PCB Polyclonal Antibody, 50ul Bottles As is typical for genesPC encodes pyruvate carboxylase, which requires biotin and ATP to catalyse the carboxylation of pyruvate to oxaloacetate. The active enzyme is a homotetramer arranged in a tetrahedron which is located exclusively in the mitochondrial matrix. Pyruvate carboxylase is involved in gluconeogenesis, lipogenesis, insulin secretion and synthesis of the neurotransmitter glutamate. Mutations in this gene have been associated with pyruvate carboxylase

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