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Presenilin 2(Phospho Ser330) Polyclonal Antibody, 50ul Cell Screening and Imaging Easy to operate

SKU: 74660655468

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Presenilin 2(Phospho Ser330) Polyclonal Antibody, 50ul Cell Screening and Imaging Easy to operateAlzheimer's disease (AD) patients with an inherited form of the disease carry mutations in the presenilin proteins (PSEN1 or PSEN2) or the amyloid precursor protein (APP). These disease linked mutations result in increased production of the longer form of amyloid beta (main component of amyloid deposits found in AD brains). Presenilins are postulated to regulate APP processing through their effects on gamma secretase, an enzyme that cleaves APP. Also,

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Description

Easy to operate

Mutations in this gene have been associated with Andersen syndrome

The protein encoded by this gene is chemotactic for skin-associated memory T lymphocytes

|subcellular location:Present in lipid rafts

Presenilin 2(Phospho Ser330) Polyclonal Antibody, 50ul Cell Screening and Imaging Easy to operateAlzheimer's disease (AD) patients with an inherited form of the disease carry mutations in the presenilin proteins (PSEN1 or PSEN2) or the amyloid precursor protein (APP). These disease linked mutations result in increased production of the longer form of amyloid beta (main component of amyloid deposits found in AD brains). Presenilins are postulated to regulate APP processing through their effects on gamma secretase, an enzyme that cleaves APP. Also,

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