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GADD34 Polyclonal Antibody, 50ul Digital Burette Two transcript variants encoding different

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GADD34 Polyclonal Antibody, 50ul Digital Burette Two transcript variants encoding differentThis gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA damaging agents. The induction of this gene by ionizing radiation occurs in certain cell lines regardless of p53 status, and its protein response is correlated with apoptosis following ionizing radiation.

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Description

Two transcript variants encoding different isoforms have been found for this gene

IL13 and IL5 are found to be regulated coordinately by several long-range regulatory elements in an over 120 kilobase range on the chromosome

Increased expression of this gene results in decreased mitochondrial leucine tRNA levels

including type II diabetes

GADD34 Polyclonal Antibody, 50ul Digital Burette Two transcript variants encoding differentThis gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA damaging agents. The induction of this gene by ionizing radiation occurs in certain cell lines regardless of p53 status, and its protein response is correlated with apoptosis following ionizing radiation.

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