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CCNK Polyclonal Antibody, 50ul Vacuum Aspirator CMTM5 encodes a member of

SKU: 75047940271

4.9
PLN185.00 PLN234.00

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CCNK Polyclonal Antibody, 50ul Vacuum Aspirator CMTM5 encodes a member ofThe protein encoded by this gene is a member of the transcription cyclin family. These cyclins may regulate transcription through their association with and activation of cyclin dependent kinases (CDK) that phosphorylate the C terminal domain (CTD) of the large subunit of RNA polymerase II. This gene product may play a dual role in regulating CDK and RNA polymerase II activities.

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Description

CMTM5 encodes a member of the chemokine-like factor superfamily

Mediator of RNA polymerase II transcription subunit 1 encoded by MED1 is a subunit of the CRSP (cofactor required for SP1 activation) complex

The encoded protein has no DNA binding activity and therefore can inhibit the DNA binding and transcriptional activation ability of basic HLH proteins with which it interacts

Allelic variants of this gene are associated with microcephaly

CCNK Polyclonal Antibody, 50ul Vacuum Aspirator CMTM5 encodes a member ofThe protein encoded by this gene is a member of the transcription cyclin family. These cyclins may regulate transcription through their association with and activation of cyclin dependent kinases (CDK) that phosphorylate the C terminal domain (CTD) of the large subunit of RNA polymerase II. This gene product may play a dual role in regulating CDK and RNA polymerase II activities.

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