NGF Polyclonal Antibody, 20ul[BT-AP06008] Drying & Desiccation and programmed cell death

and programmed cell death

GAS8 includes 11 exons spanning 25 kb and maps to a region of chromosome 16 that is sometimes deleted in breast and prostrate cancer

As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins

resulting in four separate mRNA transcripts

NGF Polyclonal Antibody, 20ul[BT-AP06008] Drying & Desiccation and programmed cell deathNGF is a member of the NGF beta family and encodes a secreted protein which homodimerizes and is incorporated into a larger complex. Nerve growth factorp has nerve growth stimulating activity and the complex is involved in the regulation of growth and the differentiation of sympathetic and certain sensory neurons. Mutations in NGF have been associated with hereditary sensory and autonomic neuropathy, type 5 (HSAN5), and dysregulation of NGF's