HLAG Polyclonal Antibody, 100ul Bottle-Top Dispenser Defects in PEX19 are a

Defects in PEX19 are a cause of Zellweger syndrome (ZWS)

and colon cancers

Required for consolidation of synaptic plasticity as well as formation of long-term memory

Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia

HLAG Polyclonal Antibody, 100ul Bottle-Top Dispenser Defects in PEX19 are aHLA G belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta 2 microglobulin). The heavy chain is anchored in the membrane. HLA G is expressed on fetal derived placental cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domain, which both bind the peptide,