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NDE1 Polyclonal Antibody, 100ul Cell Culture & Maintenance Multiple processed pseudogenes derived from

SKU: 7567306061

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NDE1 Polyclonal Antibody, 100ul Cell Culture & Maintenance Multiple processed pseudogenes derived fromThis gene encodes a member of the nuclear distribution E (NudE) family of proteins. The encoded protein is localized at the centrosome and interacts with other centrosome components as part of a multiprotein complex that regulates dynein function. This protein plays an essential role in microtubule organization, mitosis and neuronal migration. Mutations in this gene cause lissencephaly 4, a disorder characterized by lissencephaly, severe brain

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Description

Multiple processed pseudogenes derived from this gene are present in the genome

L-plastin has been found in many types of malignant human cells of non-hemopoietic origin suggesting that its expression is induced accompanying tumorigenesis in solid tissues

This gene encodes one of the five subunits of the slowly inactivating L-type voltage-dependent calcium channel in skeletal muscle cells

and this interaction may play a role in ovulation and fertilization

NDE1 Polyclonal Antibody, 100ul Cell Culture & Maintenance Multiple processed pseudogenes derived fromThis gene encodes a member of the nuclear distribution E (NudE) family of proteins. The encoded protein is localized at the centrosome and interacts with other centrosome components as part of a multiprotein complex that regulates dynein function. This protein plays an essential role in microtubule organization, mitosis and neuronal migration. Mutations in this gene cause lissencephaly 4, a disorder characterized by lissencephaly, severe brain

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