Smad4 Polyclonal Antibody, 100ul Filtration LXRA (NR1H3

LXRA (NR1H3

The encoded protein tranduces signals to other proteins after activation by a hedgehog protein/patched protein complex

this enzyme has an N-terminal domain with guanine nucleotide exchange (GEF) activity

Individuals homozygous for a mutation in this gene are at higher risk for type 2 diabetes and have higher levels of circulating glucose and insulin levels after glucose ingestion

Smad4 Polyclonal Antibody, 100ul Filtration LXRA (NR1H3SMAD4 encodes a member of the Smad family of signal transduction proteins. Smad proteins are phosphorylated and activated by transmembrane serine threonine receptor kinases in response to TGF beta signaling. The product of SMAD4 forms homomeric complexes and heteromeric complexes with other activated Smad proteins, which then accumulate in the nucleus and regulate the transcription of target genes. This protein binds to DNA and recognizes an 8 bp