Calpain 12 Polyclonal Antibody, 50ul Peripheral Blood Separation Tube HECT domain E3 ubiquitin ligases

HECT domain E3 ubiquitin ligases transfer ubiquitin from E2 ubiquitin-conjugating enzymes to protein substrates| thus targeting specific proteins for lysosomal degradation

Mutations in this gene may be associated with Parkinson disease

and also a C-terminal domain which resembles enoyl-CoA-isomerase

Cerebellin 1

Calpain 12 Polyclonal Antibody, 50ul Peripheral Blood Separation Tube HECT domain E3 ubiquitin ligasesThe calpains, calcium activated neutral proteases, are nonlysosomal, intracellular cysteine proteases. The mammalian calpains include ubiquitous, stomach specific, and muscle specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large, catalytic subunits associated with a common small, regulatory subunit. This gene encodes a member of the calpain large subunit family.