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ARK-1 Polyclonal Antibody, 100ul[BT-AP00611] Buffer Solutions POU5F1 can participate in a

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ARK-1 Polyclonal Antibody, 100ul[BT-AP00611] Buffer Solutions POU5F1 can participate in aThe protein encoded by AURKA is a cell cycle regulated kinase that appears to be involved in microtubule formation and or stabilization at the spindle pole during chromosome segregation. The encoded protein (aurora kinase A) is found at the centrosome in interphase cells and at the spindle poles in mitosis. AURKA may play a role in tumor development and progression. A processed pseudogene of AURKA has been found on chromosome 1, and an unprocessed

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Description

POU5F1 can participate in a translocation with the Ewing's sarcoma gene on chromosome 21

The activation of this kinase requires its phosphorylation by upstream kinases

This protein is initially found in the cytoplasm but is translocated into the nucleus upon phosphorylation

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ARK-1 Polyclonal Antibody, 100ul[BT-AP00611] Buffer Solutions POU5F1 can participate in aThe protein encoded by AURKA is a cell cycle regulated kinase that appears to be involved in microtubule formation and or stabilization at the spindle pole during chromosome segregation. The encoded protein (aurora kinase A) is found at the centrosome in interphase cells and at the spindle poles in mitosis. AURKA may play a role in tumor development and progression. A processed pseudogene of AURKA has been found on chromosome 1, and an unprocessed

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