Nibrin(Phospho Ser278) Polyclonal Antibody, 50ul Human Genome Knockout Libraries The genes in this group

The genes in this group respond to environmental stresses by mediating activation of the p38/JNK pathway

This complex functions in the transfer of electrons from NADH to the respiratory chain

The encoded protein has an EGF-like calcium binding domain and a seven transmembrane domain in the N-terminal region of the protein

In the elongating spermatid it is associated with the manchette

Nibrin(Phospho Ser278) Polyclonal Antibody, 50ul Human Genome Knockout Libraries The genes in this groupMutations in this gene are associated with Nijmegen breakage syndrome an autosomal recessive chromosomal instability syndrome characterized by microcephaly growth retardation immunodeficiency and cancer predisposition. The encoded protein is a member of the MRE11 RAD50 double strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double strand break repair and DNA damage induced checkpoint