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SCN1B Polyclonal Antibody, 100ul Gene Editing including osteogenesis and bone resorption

SKU: 77107889640

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SCN1B Polyclonal Antibody, 100ul Gene Editing including osteogenesis and bone resorptionVoltage gated sodium channels are heteromeric proteins that function in the generation and propagation of action potentials in muscle and neuronal cells. They are composed of one alpha and two beta subunits, where the alpha subunit provides channel activity and the beta 1 subunit modulates the kinetics of channel inactivation. This gene encodes a sodium channel beta 1 subunit. Mutations in this gene result in generalized epilepsy with febrile seizures

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Description

including osteogenesis and bone resorption

and it plays an important role in the signaling cascades leading to insulin secretion

Alternative splicing of this gene results in two transcript variants encoding different isoforms

Forms a ternary complex with NF2/merlin and GRB2

SCN1B Polyclonal Antibody, 100ul Gene Editing including osteogenesis and bone resorptionVoltage gated sodium channels are heteromeric proteins that function in the generation and propagation of action potentials in muscle and neuronal cells. They are composed of one alpha and two beta subunits, where the alpha subunit provides channel activity and the beta 1 subunit modulates the kinetics of channel inactivation. This gene encodes a sodium channel beta 1 subunit. Mutations in this gene result in generalized epilepsy with febrile seizures

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