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Integrin beta 1(Phospho Tyr795) Polyclonal Antibody, 100ul Lentiviral Packaging disease:Defects in COL4A1 are a

SKU: 77385462449

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Integrin beta 1(Phospho Tyr795) Polyclonal Antibody, 100ul Lentiviral Packaging disease:Defects in COL4A1 are aIntegrins are heterodimeric proteins made up of alpha and beta subunits. At least 18 alpha and 8 beta subunits have been described in mammals. Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metastatic diffusion of tumor cells. This gene encodes a beta subunit. Multiple alternatively spliced transcript variants

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Description

disease:Defects in COL4A1 are a cause of brain small vessel disease with hemorrhage

The encoded protein associates with RNA polymerase II and is recruited to the U1 and U2 small nuclear RNA genes

Mutations in this gene have been associated with dystonia

Shorter isoforms of this protein which lack the C-terminal HECT domain are therefore unlikely to bind E2 enzymes

Integrin beta 1(Phospho Tyr795) Polyclonal Antibody, 100ul Lentiviral Packaging disease:Defects in COL4A1 are aIntegrins are heterodimeric proteins made up of alpha and beta subunits. At least 18 alpha and 8 beta subunits have been described in mammals. Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metastatic diffusion of tumor cells. This gene encodes a beta subunit. Multiple alternatively spliced transcript variants

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