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UBA1 Polyclonal Antibody, 20ul Molecular Sciences Mutations in this gene have

UBA1 Polyclonal Antibody, 20ul Molecular Sciences Mutations in this gene have

Name: UBA1 Polyclonal Antibody, 20ul Molecular Sciences Mutations in this gene have
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UBA1 Polyclonal Antibody, 20ul Molecular Sciences Mutations in this gene haveUbiquitin like modifier activating enzyme 1 encoded by UBA1 catalyzes the first step in ubiquitin conjugation to mark cellular proteins for degradation. This gene complements an X linked mouse temperature sensitive defect in DNA synthesis, and thus may function in DNA repair. It is part of a gene cluster on chromosome Xp11. 3. Alternatively spliced transcript variants that encode the same protein have been described.

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Description

Mutations in this gene have been associated with idiopathic cardiomyopathy (IDC)

and thus suppresses apoptosis

Exhibits heparin-binding activity

Among its related pathways are Axon guidance

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