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Human Nucleophosmin, NPM1 ELISA Kit , 96T Gene Synthesis Defects in this gene are

SKU: 77525618680

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Human Nucleophosmin, NPM1 ELISA Kit , 96T Gene Synthesis Defects in this gene areInvolved in diverse cellular processes such as ribosome biogenesis, centrosome duplication, protein chaperoning, histone assembly, cell proliferation, and regulation of tumor suppressors p53 TP53 and ARF. Binds ribosome presumably to drive ribosome nuclear export. Associated with nucleolar ribonucleoprotein structures and bind single stranded nucleic acids. Acts as a chaperonin for the core histones H3, H2B and H4. Stimulates APEX1 endonuclease

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Description

Defects in this gene are a cause of isolated microphthalmia with cataract type 2 (MCOPCT2)

In the developing nervous system AKT is a critical mediator of growth factor-induced neuronal survival

Mutations in this gene have been associated with medulloblastomas

The gene encoding LRRK1

Human Nucleophosmin, NPM1 ELISA Kit , 96T Gene Synthesis Defects in this gene areInvolved in diverse cellular processes such as ribosome biogenesis, centrosome duplication, protein chaperoning, histone assembly, cell proliferation, and regulation of tumor suppressors p53 TP53 and ARF. Binds ribosome presumably to drive ribosome nuclear export. Associated with nucleolar ribonucleoprotein structures and bind single stranded nucleic acids. Acts as a chaperonin for the core histones H3, H2B and H4. Stimulates APEX1 endonuclease

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