MARCKS(Phospho-Ser167/170) Rabbit Polyclonal Antibody, 50ul Buffers & Solutions It also contains a destruction

It also contains a destruction box (D box) that is required for its degradation by the APC

and has in vitro anticoagulant activity and also inhibits phospholipase A2 activity

It was found to be one of the mitochondrial matrix proteins that are preferentially degraded by the serine protease 15(PRSS15)

The protein encoded by this gene contains a GTPase-activating protein domain

MARCKS(Phospho-Ser167/170) Rabbit Polyclonal Antibody, 50ul Buffers & Solutions It also contains a destructionThe protein encoded by this gene is a substrate for protein kinase C. It is localized to the plasma membrane and is an actin filament crosslinking protein. Phosphorylation by protein kinase C or binding to calcium calmodulin inhibits its association with actin and with the plasma membrane leading to its presence in the cytoplasm. The protein is thought to be involved in cell motility phagocytosis membrane trafficking and mitogenesis.