Tuberin Polyclonal Antibody, 50ul[BT-AP09287] Cell Function Analysis The protein encoded by this

The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription

The functions of human sirtuins have not yet been determined

Alternate splicing of this gene results in several transcript variants encoding different isoforms

This protein plays a role in the formation and maintenance of adult intestinal stem cells during postembryonic development

Tuberin Polyclonal Antibody, 50ul[BT-AP09287] Cell Function Analysis The protein encoded by thisMutations in TSC2 lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms.