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NPC1 Rabbit Polyclonal Antibody, 20ul Plasmid Preparation blocking interaction with the signal

SKU: 77842580796

4.7
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NPC1 Rabbit Polyclonal Antibody, 20ul Plasmid Preparation blocking interaction with the signalThis gene encodes a large protein that resides in the limiting membrane of endosomes and lysosomes and mediates intracellular cholesterol trafficking via binding of cholesterol to its N terminal domain. It is predicted to have a cytoplasmic C terminus 13 transmembrane domains and 3 large loops in the lumen of the endosome the last loop being at the N terminus. This protein transports low density lipoproteins to late endosomal lysosomal compartments

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Description

blocking interaction with the signal recognition particle (SRP) and preventing mistranslocation to the endoplasmic reticulum

Interacts with ELF3

encoded by PHKB (phosphorylase kinase regulatory subunit beta)

CdcA3 is involved in ubiquination and degradation of the mitosis-inhibitory kinase Wee 1

NPC1 Rabbit Polyclonal Antibody, 20ul Plasmid Preparation blocking interaction with the signalThis gene encodes a large protein that resides in the limiting membrane of endosomes and lysosomes and mediates intracellular cholesterol trafficking via binding of cholesterol to its N terminal domain. It is predicted to have a cytoplasmic C terminus 13 transmembrane domains and 3 large loops in the lumen of the endosome the last loop being at the N terminus. This protein transports low density lipoproteins to late endosomal lysosomal compartments

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