Phospho-ALK (Y1096) Polyclonal Antibody, 50ul In vitro Assessment but unlike BRCA1

but unlike BRCA1

This protein has E3 ligase activity conferred by a plant homeodomain (PHD) in its N-terminus and phospho-kinase activity conferred by a kinase domain in its C-terminus

this protein interacts with BRCA1 and is phosphorylated by ATM

Gene expression is high during fetal development and in most tumors

Phospho-ALK (Y1096) Polyclonal Antibody, 50ul In vitro Assessment but unlike BRCA1ALK encodes a receptor tyrosine kinase, which belongs to the insulin receptor superfamily. ALK tyrosine kinase receptor comprises an extracellular domain, an hydrophobic stretch corresponding to a single pass transmembrane region, and an intracellular kinase domain. It plays an important role in the development of the brain and exerts its effects on specific neurons in the nervous system. This gene has been found to be rearranged, mutated, or