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Caspase-1 Polyclonal Antibody, 100ul[BT-AP01193] Pipette Filler Activated C1 cleaves C2 into

SKU: 78039218657

4.3
EUR141.00 EUR174.00

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Caspase-1 Polyclonal Antibody, 100ul[BT-AP01193] Pipette Filler Activated C1 cleaves C2 intoCASP1 encodes a protein (caspase 1) which is a member of the cysteine aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme. This gene was identified by its ability to proteolytically

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Description

Activated C1 cleaves C2 into C2a and C2b

characterized by the lack of the A subunit alone

which is essential for the catalytic activity

The protein localizes primarily to the nucleus and its expression is developmentally regulated

Caspase-1 Polyclonal Antibody, 100ul[BT-AP01193] Pipette Filler Activated C1 cleaves C2 intoCASP1 encodes a protein (caspase 1) which is a member of the cysteine aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme. This gene was identified by its ability to proteolytically

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