BLM Polyclonal Antibody, 20ul Vacuum Filter Alternate splicing of this gene

Alternate splicing of this gene results in two transcript variants encoding different isoforms

Cadherin domains occur as repeats in the extracellular region and are thought to contribute to the sorting of heterogeneous cell types and the maintenance of orderly structures such as epithelium

suggesting that several different adenylate cyclases may couple to olfactory receptors and that there may be multiple receptor-mediated mechanisms for the generation of cAMP signals

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BLM Polyclonal Antibody, 20ul Vacuum Filter Alternate splicing of this geneThe Bloom syndrome gene product is related to the RecQ subset of DExH box containing DNA helicases and has both DNA stimulated ATPase and ATP dependent DNA helicase activities. Mutations causing Bloom syndrome delete or alter helicase motifs and may disable the 3' 5' helicase activity. The normal protein may act to suppress inappropriate recombination.