IKappaB-Epsilon Polyclonal Antibody, 50ul ROS/Nitric Oxide Detection and these isoforms may differ

and these isoforms may differ in the post-translational modifications that occur at the N-terminus of some isoforms

the encoded protein accumulates in the nucleus and binds the tumor suppressor protein p53

The protein encoded by this gene binds to the fibronectin type III domains of ITGB4 and may help link ITGB4 to the intermediate filament cytoskeleton

the minichromosome maintenance proteins (MCMs) and DNA polymerase

IKappaB-Epsilon Polyclonal Antibody, 50ul ROS/Nitric Oxide Detection and these isoforms may differThe protein encoded by NFKBIE binds to components of NF kappa B, trapping the complex in the cytoplasm and preventing it from activating genes in the nucleus. Phosphorylation of the encoded protein targets it for destruction by the ubiquitin pathway, which activates NF kappa B by making it available to translocate to the nucleus.