GATA-2/3 Polyclonal Antibody, 20ul Protein Expression The receptors are seven-pass transmembrane

The receptors are seven-pass transmembrane proteins that respond to extracellular cues and activate intracellular signal transduction pathways

They participate in two different transcriptional regulation processes

Defects in ATG16L1 are a cause of susceptibility to inflammatory bowel disease type 10 (IBD10)

which form a tetrameric holoenzyme

GATA-2/3 Polyclonal Antibody, 20ul Protein Expression The receptors are seven-pass transmembraneGATA3 encodes GATA binding protein 3 which belongs to the GATA family of transcription factors. The protein contains two GATA type zinc fingers and is an important regulator of T cell development and plays an important role in endothelial cell biology. Defects in this gene are the cause of hypoparathyroidism with sensorineural deafness and renal dysplasia.