PACS1 Polyclonal Antibody, 50ul In vitro Assessment hypophosphorylated form of the protein

hypophosphorylated form of the protein binds transcription factor E2F1

This gene encodes a member of a subfamily of LIM domain proteins that are characterized by an N-terminal proline-rich region and three C-terminal LIM domains

and signal transducers to form a large multi-subunit protein complex known as the BRCA1-associated genome surveillance complex (BASC)

Additional transcript variants have been described

PACS1 Polyclonal Antibody, 50ul In vitro Assessment hypophosphorylated form of the proteinThis gene encodes a protein with a putative role in the localization of trans Golgi network (TGN) membrane proteins. Mouse and rat homologs have been identified and studies of the homologous rat protein indicate a role in directing TGN localization of furin by binding to the protease's phosphorylated cytosolic domain. In addition, the human protein plays a role in HIV 1 Nef mediated downregulation of cell surface MHC I molecules to the TGN, thereby