SH2D3 Polyclonal Antibody, 100ul Miscellaneous |Belongs to the peptidase M28

|Belongs to the peptidase M28 family

which are both disorders of the peripheral nervous system

It plays a negative regulatory role in the Ras-Raf1-MAPK pathway| and knockout mice have been shown to develop spontaneous tumors| suggesting a role as a tumor suppressor gene

The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete

SH2D3 Polyclonal Antibody, 100ul Miscellaneous |Belongs to the peptidase M28This gene encodes an adaptor protein and member of a cytoplasmic protein family involved in cell migration. The encoded protein contains a putative Src homology 2 (SH2) domain and guanine nucleotide exchange factor like domain which allows this signaling protein to form a complex with scaffolding protein Crk associated substrate. Multiple transcript variants encoding different isoforms have been found for this gene.