Oct-3/4 Polyclonal Antibody, 50ul[BT-AP06332] Multi-Layer Cell Culture System Eight transcript variants encoding the

Eight transcript variants encoding the same protein have been found for this gene

In vitro assays indicate the protein lacks phosphorylation activity

thereby playing a key role in regulating the cellular redox environment

This protein and RII PKA colocalize at the cell periphery

Oct-3/4 Polyclonal Antibody, 50ul[BT-AP06332] Multi-Layer Cell Culture System Eight transcript variants encoding thePOU5F1 (POU class 5 homeobox 1) encodes a transcription factor containing a POU homeodomain that plays a key role in embryonic development and stem cell pluripotency. Aberrant expression of POU5F1 in adult tissues is associated with tumorigenesis. POU5F1 can participate in a translocation with the Ewing's sarcoma gene on chromosome 21, which also leads to tumor formation. Alternative splicing, as well as usage of alternative AUG and non AUG