FDFT Rabbit Polyclonal Antibody, 50ul Digital Burette Members of the glypican-related integral

Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage

the active protein has an opportunity to diffuse away from the receptor and deliver its message for a prolonged period to its downstream target

The lack of a similar gene in mouse results in growth retardation

Mutations in this gene are associated with limb-girdle muscular dystrophies type 2A

FDFT Rabbit Polyclonal Antibody, 50ul Digital Burette Members of the glypican-related integralThis gene encodes a membrane associated enzyme located at a branch point in the mevalonate pathway. The encoded protein is the first specific enzyme in cholesterol biosynthesis catalyzing the dimerization of two molecules of farnesyl diphosphate in a two step reaction to form squalene.