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NTCP2 Rabbit Polyclonal Antibody, 50ul Polyclonal Antibody Preparation This protein kinase is calcium-independent

SKU: 80668989068

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NTCP2 Rabbit Polyclonal Antibody, 50ul Polyclonal Antibody Preparation This protein kinase is calcium-independentThis gene encodes a sodium bile acid cotransporter. This transporter is the primary mechanism for uptake of intestinal bile acids by apical cells in the distal ileum. Bile acids are the catabolic product of cholesterol metabolism so this protein is also critical for cholesterol homeostasis. Mutations in this gene cause primary bile acid malabsorption (PBAM); muatations in this gene may also be associated with other diseases of the liver and intestines

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Description

This protein kinase is calcium-independent and phospholipid-dependent

TAS2R44 belongs to the large TAS2R receptor family

Sequence analysis identified multiple transcript variants encodin

Binds to F-actin but not to RNA

NTCP2 Rabbit Polyclonal Antibody, 50ul Polyclonal Antibody Preparation This protein kinase is calcium-independentThis gene encodes a sodium bile acid cotransporter. This transporter is the primary mechanism for uptake of intestinal bile acids by apical cells in the distal ileum. Bile acids are the catabolic product of cholesterol metabolism so this protein is also critical for cholesterol homeostasis. Mutations in this gene cause primary bile acid malabsorption (PBAM); muatations in this gene may also be associated with other diseases of the liver and intestines

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