HNF-1Beta Polyclonal Antibody, 100ul Centrifuges hypomethylation of the CAGE promoter

hypomethylation of the CAGE promoter region is associated with tumor progression and may serve as a valuable marker in cancer diagnosis

The encoded protein is involved in protein trafficking from early to late endosomes via vesicle fusion and exocytosis

DCTN2 encodes a 50-kD subunit of dynactin

It plays a negative regulatory role in the Ras-Raf1-MAPK pathway

HNF-1Beta Polyclonal Antibody, 100ul Centrifuges hypomethylation of the CAGE promoterHNF1B encodes a member of the homeodomain containing superfamily of transcription factors. Hepatocyte nuclear factor 1 beta binds to DNA as either a homodimer, or a heterodimer with the related protein hepatocyte nuclear factor 1 alpha. The gene has been shown to function in nephron development, and regulates development of the embryonic pancreas. Mutations in this gene result in renal cysts and diabetes syndrome and noninsulin dependent diabetes