LIF Polyclonal Antibody, 100ul Antisense Oligonucleotides Mutations in TUBA1A cause lissencephaly

Mutations in TUBA1A cause lissencephaly type 3 (LIS3) - a neurological condition characterized by microcephaly

Knockout studies in mice suggest that this gene plays a role in T-helper cell activation| and may be involved in inflammation and immune regulation

A similar protein in rats may play a role in the regulation of cell differentiation

The corresponding rat protein has been detected in the pancreas

LIF Polyclonal Antibody, 100ul Antisense Oligonucleotides Mutations in TUBA1A cause lissencephalyLeukemia inhibitory factor encoded by LIF is a pleiotropic cytokine with roles in several different systems. It is involved in the induction of hematopoietic differentiation in normal and myeloid leukemia cells, induction of neuronal cell differentiation, regulator of mesenchymal to epithelial conversion during kidney development, and may also have a role in immune tolerance at the maternal fetal interface. Alternatively spliced transcript variants