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MYOC Polyclonal Antibody, 50ul Custom DNA Oligos Transcript variants utilizing alternative polyA

SKU: 81122206497

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MYOC Polyclonal Antibody, 50ul Custom DNA Oligos Transcript variants utilizing alternative polyAMYOC encodes the protein myocilin, which is believed to have a role in cytoskeletal function. MYOC is expressed in many occular tissues, including the trabecular meshwork, and was revealed to be the trabecular meshwork glucocorticoid inducible response protein (TIGR). The trabecular meshwork is a specialized eye tissue essential in regulating intraocular pressure, and mutations in MYOC have been identified as the cause of hereditary juvenile onset

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Description

Transcript variants utilizing alternative polyA signals and alternative 5'-terminal exons exist but all encode the same protein

growth retardation

Alternatively spliced transcript variants encoding distinct isoforms have been found for GOSR1

Mutation in this gene are associated with both Jervell and Lange-Nielsen and Romano-Ward forms of long-QT syndrome

MYOC Polyclonal Antibody, 50ul Custom DNA Oligos Transcript variants utilizing alternative polyAMYOC encodes the protein myocilin, which is believed to have a role in cytoskeletal function. MYOC is expressed in many occular tissues, including the trabecular meshwork, and was revealed to be the trabecular meshwork glucocorticoid inducible response protein (TIGR). The trabecular meshwork is a specialized eye tissue essential in regulating intraocular pressure, and mutations in MYOC have been identified as the cause of hereditary juvenile onset

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