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MDM2 Polyclonal Antibody, 100ul[BT-AP05300] Multiplex Immunoassays Data suggest that the similar

SKU: 81942582990

4.3
PLN123.75 PLN165.75

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MDM2 Polyclonal Antibody, 100ul[BT-AP05300] Multiplex Immunoassays Data suggest that the similarMDM2 encodes a nuclear localized E3 ubiquitin ligase. E3 ubiquitin protein ligase Mdm2 can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. MDM2 is itself transcriptionally regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript

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Description

Data suggest that the similar protein in mouse plays an important role in trabeculation of the embryonic heart

an apoptosis-promoting nuclear RNA-binding protein

Mouse studies suggest that this gene may serve as a functional substitute for the dystrophin gene and therefore

also known as F-actin bundling domain

MDM2 Polyclonal Antibody, 100ul[BT-AP05300] Multiplex Immunoassays Data suggest that the similarMDM2 encodes a nuclear localized E3 ubiquitin ligase. E3 ubiquitin protein ligase Mdm2 can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. MDM2 is itself transcriptionally regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript

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