HERC3 Rabbit Polyclonal Antibody, 20ul Drug Development and Evaluation and CC3 (CC for conserved

and CC3 (CC for conserved cytoplasmic)

This enzyme is highly expressed in pregnant uterus

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Mutations in this gene are associated with autosomal dominant progressive external ophthalmoplegia-6 (PEOA6) and Seckel syndrome 8

HERC3 Rabbit Polyclonal Antibody, 20ul Drug Development and Evaluation and CC3 (CC for conservedThis gene encodes a member the HERC ubiquitin ligase family. The encoded protein is located in the cytosol and binds ubiquitin via a HECT domain. Mutations in this gene have been associated with colorectal and gastric carcinomas. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.