JAK3 Polyclonal Antibody, 100ul Glassware Interacts with SNRNP70 in apoptotic

Interacts with SNRNP70 in apoptotic cells (By similarity)

Mutations in PMS2 have been associated with hereditary nonpolyposis colorectal cancer (HNPCC

and may play an important role in nervous system development

TRAF adaptor proteins have been shown to bind to this receptor and transduce the signals leading to activation of NF-kappaB

JAK3 Polyclonal Antibody, 100ul Glassware Interacts with SNRNP70 in apoptoticThe protein encoded by JAK3 is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease).