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NCoA-5 Polyclonal Antibody, 20ul Molecular Biology A pathogenic role for this

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NCoA-5 Polyclonal Antibody, 20ul Molecular Biology A pathogenic role for thisNCOA5 (nuclear receptor coactivator 5) encodes a coregulator for the alpha and beta estrogen receptors and the orphan nuclear receptor NR1D2. The protein localizes to the nucleus, and is thought to have both coactivator and corepressor functions. Its interaction with nuclear receptors is independent of the AF2 domain on the receptors, which is known to regulate interaction with other coreceptors. Two alternatively spliced transcript variants for this

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Description

A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantigen and an autoreactive T cell target in insulin-dependent diabetes

colorectal

an N-linked glycan-processing enzyme in the endoplasmic reticulum

Calcium-activated potassium channel subunit beta-4 encoded by KCNMB4 is an auxiliary beta subunit which slows activation kinetics

NCoA-5 Polyclonal Antibody, 20ul Molecular Biology A pathogenic role for thisNCOA5 (nuclear receptor coactivator 5) encodes a coregulator for the alpha and beta estrogen receptors and the orphan nuclear receptor NR1D2. The protein localizes to the nucleus, and is thought to have both coactivator and corepressor functions. Its interaction with nuclear receptors is independent of the AF2 domain on the receptors, which is known to regulate interaction with other coreceptors. Two alternatively spliced transcript variants for this

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