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DNA-PKCS Polyclonal Antibody, 20ul[BT-AP02674] Polyclonal Antibody Preparation Mice lacking this gene show

SKU: 83335250210

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DNA-PKCS Polyclonal Antibody, 20ul[BT-AP02674] Polyclonal Antibody Preparation Mice lacking this gene showPRKDC (protein kinase, DNA activated, catalytic polypeptide) encodes the catalytic subunit of the DNA dependent protein kinase (DNA PK). It functions with the Ku70 Ku80 heterodimer protein in DNA double strand break repair and recombination. The protein encoded is a member of the PI3 PI4 kinase family.

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Description

Mice lacking this gene show a severe impairment in the migration and homing of lymphocytes

DNA pol Ω is ubiquitously expressed in various tissues and mediates the cellular mechanism of damage-induced mutagenesis

CASP2 (caspase 2) encodes a member of the cysteine-aspartic acid protease (caspase) family

and has been shown to regulate the helicase activity of the complex

DNA-PKCS Polyclonal Antibody, 20ul[BT-AP02674] Polyclonal Antibody Preparation Mice lacking this gene showPRKDC (protein kinase, DNA activated, catalytic polypeptide) encodes the catalytic subunit of the DNA dependent protein kinase (DNA PK). It functions with the Ku70 Ku80 heterodimer protein in DNA double strand break repair and recombination. The protein encoded is a member of the PI3 PI4 kinase family.

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