ILK Polyclonal Antibody, 50ul Tubes Defects in CNGB1 are a

Defects in CNGB1 are a cause of cause of retinitis pigmentosa type 45

Contains 1 PDZ (DHR) domain

The protein encoded by this gene is localized to the cytoplasmic face of the nuclear pore complex where it is required for proper cell cycle progression and nucleocytoplasmic transport

|Contains 2 cystatin domains

ILK Polyclonal Antibody, 50ul Tubes Defects in CNGB1 are aILK encodes a protein with a kinase like domain and four ankyrin like repeats. The encoded protein associates at the cell membrane with the cytoplasmic domain of beta integrins, where it regulates integrin mediated signal transduction. Activity of this protein is important in the epithelial to mesenchymal transition, and over expression of this gene is implicated in tumor growth and metastasis. Alternative splicing results in multiple transcript