UBP14 Polyclonal Antibody, 100ul Buffer Solutions and two short complement-like repeats

and two short complement-like repeats

The protein is expressed in the photoreceptor layer of the retina| and the gene is mutated in autosomal recessive retinitis pigmentosa

including platelet dense granules and melanosomes

This gene was identified upon genomic analysis of a gene-dense region at human chromosome 12p13

UBP14 Polyclonal Antibody, 100ul Buffer Solutions and two short complement-like repeatsThis gene encodes a member of the ubiquitin specific processing (UBP) family of proteases that is a deubiquitinating enzyme (DUB) with His and Cys domains. This protein is located in the cytoplasm and cleaves the ubiquitin moiety from ubiquitin fused precursors and ubiquitinylated proteins. Mice with a mutation that results in reduced expression of the ortholog of this protein are retarded for growth, develop severe tremors by 2 to 3 weeks of age