c-Myb (Acetyl Lys480) Rabbit Polyclonal Antibody, 100ul Mechanical Pipette Mutations in KRT8 cause cryptogenic

Mutations in KRT8 cause cryptogenic cirrhosis

exons 2 and 3 encode the alpha1 and alpha2 domain

The encoded protein contains multiple conserved functional domains

The protein encoded by DOK2 (docking protein 2)is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase

c-Myb (Acetyl Lys480) Rabbit Polyclonal Antibody, 100ul Mechanical Pipette Mutations in KRT8 cause cryptogenicComprised of 3 domains; an N terminal DNA binding domain a centrally located transcriptional activation domain and a C terminal domain involved in transcriptional repression. Transcriptional activator; DNA binding protein that specifically recognize the sequence 5' YAAC