Phospho-Akt2 (S474) Polyclonal Antibody, 50ul Antibodies An important paralog of this

An important paralog of this gene is GPR162

Mutations in this gene have been associated with disruption of the retinal pigment epithelium (RPE) phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa (RP)

In conjunction with complement component 1| q subcomponent| B chain (C1QB)| this gene shows an increase in expression in melanoma cells and may serve as an accurate biomarker for the disease

5-triphosphate (PIP3)

Phospho-Akt2 (S474) Polyclonal Antibody, 50ul Antibodies An important paralog of thisAKT2 is a putative oncogene encoding a protein belonging to a subfamily of serine threonine kinases containing SH2 like (Src homology 2 like) domains. AKT2 was shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors. Overexpression contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. AKT serine threonine kinase 2 is a general protein kinase capable of